Featured

Happy Monday 13th May

Incredibly Good News:

My secondary Breast Cancer (mets to bones) diagnosis from May 2017 looks like it’s continuing to reverse itself. I appear to be on the right track to meet my outrageous goal of getting a no evidence of disease (NED) report this year. I had a bone scan last week; my first one in 5 months and the results are a great read. I especially love re-reading this line from the report:
The previously identified lesions elsewhere on the bone scan performed 6/12/18 are no longer visualized.”

So this means:
In about 4 of the 7 places, where there was some broad areas of what conventional oncologist’s call stage 4 ‘incurable’ disease, the cancer is NO LONGER DETECTED.
OMG – How wonderful is that!
I’m still swimming in the good feeling feelings of…

1) relief; Even though I believe in everything I am doing, I was a little concerned given that I’m taking very leading- edge and not always conventional approach to my healing.

2) acknowledgment; this report somehow acknowledges all my valuable time and energy devoted to this task of researching how to starve my cancer.

3) inspiration; I am feeling energized and focused on the NED goal ahead of me. I have just three areas of disease still visualized on the latest bone scan; I started with 7 bones lesions + 3 breast area/lymph node tumors 2 years ago.


If you or someone you know could use some support in learning how they could turn their cancer diagnosis around like I have these are my top 3 resource suggestions:

1) The electronic version of the book “How to Starve Cancer…” by Jane McLelland:
https://www.amazon.com.au/Starve-Cancer-without-starving-yourself-ebook/dp/B07B2XMLT9

2) The How to Starve Cancer book’s author’s Facebook Group:
https://www.facebook.com/groups/off.label.drugsforcancer/


3) My now 2000+ member strong How to Starve Cancer… Study Support Group:
https://www.facebook.com/groups/starvecancer/
The study group is in Facebook and currently in secret mode. So you will first need to find me on Facebook and make a friend request with an accompanying Facebook message that lets me know you want to join the study support group.
A reply message will come directly from me.





Featured

What I am taking and why.

A whole day’s meds and supps: Current as of June 23rd  2019

1 x capsule Milk Thistle
available online at  i-herb.com

Each capsule contains mainly Milk Thistle and a little Globe Artichoke leaf.

There appears to be many studies on Pubmed suggesting that silymarin from Milk Thistle may exert a strong anticarcinogenic effect against many types of cancer, including breast cancer. It also and anti-oxidant and protects the liver and kidneys.
Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cycli… | Clinical Cancer Research

http://clincancerres.aacrjournals.org/content/4/4/1055.short

Silibinin Suppresses EGFR Ligand-induced CD44 Expression through Inhibition of EGFR Activity in Breast Cancer Cells
http://ar.iiarjournals.org/content/31/11/3767.shor


1 x big teaspoon organic Reishi mushroom powder (1 in afternoon tea )

I buy organic powder from my favorite Australian based online herb and spice supplier: https://www.australherbs.com.au/shop/item/reishi-mushroom-powder-organic
or from i-herb.com

Ganoderma lucidum extract (GLE) impairs breast cancer stem cells by targeting the STAT3 pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267592/

Easy read on Reishi:
https://draxe.com/reishi-mushroom/


1 x Vitamin E (as d-alpha tocopherol) 400IU (1 with breakfast )

available online at  i-herb.com

I weigh 54kg so from what I can understand that means 1 a day is plenty to do the job. Someone heavier might take more each day.
Brand: A. C Grace Company ‘Unique E’ online from iherb.com

This page  summarises the findings on tocopherols being a potent aromatase inhibitor.
https://raypeatforum.com/community/threads/vitamin-e-tocopherol-is-a-potent-aromatase-inhibitor.

The mechanisms of anti-cancer activity of tocopherols 1) inhibition of ER (2) increasing peroxisome proliferator activated receptor γ (PPARγ) expression and activity, (3) induction of Nrf2, (4) antioxidative and anti-inflammatory activities, and (5) induction of apoptosis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257724/

Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-γ
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753525/


1 x Quercetin 600mg (1/2 at lunch & at dinner )

available online at  i-herb.com
Metabolic Pathway inhibitor: Glucose/Glut 1 and Fatty Acid (FAS)

Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis

https://www.nature.com/articles/srep24049

Quercetin induces apoptosis in triple-negative breast cancer cells via inhibiting fatty acid synthase and β-catenin
http://www.ijcep.com/files/ijcep0036612.pdf


1 x Berberine 500mg (with breakfast & w lunch somedays dependnig on my menu)

available online at  i-herb.com

Multi Metabolic Pathway inhibitor:
SREBP-1 Acetate
SREBP-1
Insulin
OXPHOS
mTOR
Gln OXPHOS
and supresses hedgehog signalling

Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546096/

Berberine induces apoptosis in breast cancer cells through mitochondrial-dependent pathway
https://doi.org/10.1016/j.ejphar.2010.07.037

A growing body of reports supports the evidence that berberine has anticancer effects, being able to block the proliferation of and to kill cancer cells
https://www.sciencedirect.com/science/article/abs/pii/S000629521200500X

A neo-adjuvant endocrine trial showed a significant association between the increase of SREBP1 expression and lack of clinical response, providing further support for a role of SREBP1 in the acquisition of endocrine resistance in breast cancer.
https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-018-1041-8

 

1 x Citrus Bergamot 500mg (1 whilst preparing dinner or lunch)

being Citrus Bergamia extract 500mg.  

Brand: Jarrow Formulas available online at  i-herb.com

Metabolic Pathway inhibitor: Fatty Acid/Mevolonate

Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho-GDI-signalling and mitochondrial metabolism

https://www.sciencedirect.com/science/article/pii/S0005272818300616?via%3Di&fbclid=IwAR31J5Nb1c-FMAWiEF6xHNfDOvk-LoMW53B95BBnEqtMAwsZ7vNSgW2__GI

Molecular mechanisms of lipid- and glucose-lowering activities of bergamot flavonoids
https://www.sciencedirect.com/science/article/pii/S2213434415300220
 

1 & 1/2 x Garcinia 500mg (1/2 at beginning of each main meal)

being a cut- in-half tablet of Garcinia Cambogia extract 1000mg. So I’m getting  250mg Hydroxycitric Acid (HYDROXY) ad the rest is fruit of Garcinia Cambogia.

Brand: Jarrow Formulas available online at  i-herb.com

Metabolic Pathway inhibitor: Fatty Acid/ACLY
ACLY is a cross-link between glucose metabolism and fatty acid synthesis/mevalonate pathways controlled by SREBP-1. Potently inhibited by hydroxycitrate.
ATP Citrate Lyase Inhibitors as Novel Cancer Therapeutic Agents Recent Patents on Anti-Cancer Drug Discovery, 2012, 7, 154-167


6 x Curcumin 500mg
(2 at beginning of each main meal)

being Curcumin Phytosome with Meriva 500mg
I swallow with Tulsi tea for Ursolic Acid
Brand: Jarrow Formulas
available online at  i-herb.com
I swallow my curcumin capsules with Tulsi tea in which I’ve dissolved my Hu Zang for the ursolic acid / resv / curc combo effect.
Metabolic Pathway inhibitor: Glutamine/Glutaminolysis

A combination of ursolic acid and resveratrol or ursolic acid and curcumin prevents glutamine uptake by the cancer cell.

 

Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism
https://www.nature.com/articles/s41698-017-0024-z

Unraveling the Anticancer Effect of Curcumin and Resveratrol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133053/



Ursolic Acid (1- 2 cups  at beginning & end of each main meal)

being in Tulsi Tea (aka Holy Basil Tea) available online at  i-herb.com
I swallow my Curcumin capsules (see above) with 150ml of the strong Tulsi tea
Brand: I buy organic loose tea leaves in bulk online and drink with each meal. I will mix my other herbs and ginger in it too.

Metabolic Pathway inhibitor: Glutamine/Glutaminolysis 

see above study for Curcumin combo

Ursolic acid, a potential anticancer compound for breast cancer therapy. – PubMed – NCBI
https://www.ncbi.nlm.nih.gov/pubmed/27469428

ECOTEAS Organic Tulsi | Tulsi Benefits
https://yerbamate.com/pages/tulsi-benefits



EGCG
Green Tea 150ml with breakfast and with morning tea

Brand: I buy organic green tea teabags online at  i-herb.com
Jane’s book says:
“EGCG  reduces angiogenesis and inhibitors of glutamate dehydrogenase (GHD), a precursor of glutamine (an amino acid), the other key nutrient cancer uses with glucose to fuel its growth. (
so…it’s in my map under Glutamine/Glutaminolysis)”
Mclelland, Jane. How to Starve Cancer …without starving yourself: The Discovery of a Metabolic Cocktail That Could Transform the Lives of Millions . Conscious Dreams Publishing. Kindle Edition.
More on this..
https://www.nature.com/articles/18793

And 10 health benefits of green tea supported by studies:
https://www.healthline.com/nutrition/top-10-evidence-based-health-benefits-of-green-tea#section10

1 x EGCG  capsule 98% Polyphenols (1 with dinner)

With dinner : De-caf Mega Green tea Extract 45% EGCG

Brand: Life Extension available online at  i-herb.com
Metabolic Pathway inhibitor: Glutamine/Glutaminolysis



2 x Nicotinamide / Vitamin B3 500mg
(1 with b’fast  1 x dinner)
being Nicotinamide 500mg (niacin flush-free)

 

available online at  i-herb.com

Metabolic Pathway inhibitor: Helps with all pathways in a complex manner

Reconstruction of pathway modification induced by nicotinamide using multi-omic network analyses in triple negative breast cancer
https://www.nature.com/articles/s41598-017-03322-7


Nicotinamide also protects the stomach mucus from damage caused by non-steroid anti-inflammatory drugs ( NSAIDs)

And more I’ve read on Nicotinamide / Vitamin B3

http://www.alternative-cancer-care.com/niacin-vitamin-b3-and-cancer.html?fbclid=IwAR31DQy6lWaIz3J4Or9r1Y_YIeP1mpf842KkStGTgJM-TBPXpLVN7i-8noQ



Valaciclovir 500mg x 1 with lunch

A herpes anti-viral drug prescribed by GP after I realized ( reading the book) that the cancer and virus could be closely linked.

Study shows specific type of herpes could cause breast cancer

https://www.healthimaging.com/topics/breast-imaging/study-shows-specific-type-herpes-could-cause-breast-cancer

 



1 x Dipyridamole 200mg  (1 at b’fast )
 

being 200mg (sustained release) 

Brand: Persantin available by prescription- and I was able to obtain due to it’s proven anti-viral action and my bloods showing herpes virus.
https://aac.asm.org/content/45/12/3657

Metabolic Pathway inhibitors: Glutamine/Nucleoside Salvage and the Fatty Acid/ SREBP-2

Dipyridamole is an old anti-platelet medication ( stops  blood cells sticking together and so stops them clustering and hiding cancer cells).

 

Dipyridamole starves cancer of the nucleotides and other proteins and enhances the effects of my anti-viral medication.

Selective potentiation of lometrexol growth inhibition by dipyridamole through cell-specific inhibition of hypoxanthine salvage
https://www.nature.com/articles/bjc1997552

Dipyridamole decreases platelet-derived growth factor levels in human serum.
https://www.ncbi.nlm.nih.gov/pubmed/3579723 


2 x Glucosamine Sulphate 750mg each (with lunch)
 
A matrix metallo-proteinase inhibitor available online at  i-herb.com.

Glucosamine sulfate suppresses the expression of matrix metalloproteinase-3 in osteosarcoma cells in vitro
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000453/


1g x Polygonum Cuspidatum Powder Extract  (1/3 g before each main meal)

being whole of Japanese Knotweed AKA Chinese herb Hu Zang powder 500mg dissolved in water and drunk. Metabolic Pathway inhibitors: Pentose Phosphate (P P Pathway) and likely more too. *Warning: not a safe supplement for “everyone” with breast cancer.. until you read this and your doctor agrees that it is not going to cause you harm in regards to estrogen do NOT take it:

Walking a Tightrope: A Perspective of Resveratrol Effects on Brea…: Ingenta Connect

https://www.ingentaconnect.com/content/ben/cpps/2018/00000019/00000003/art00008

A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo | Cell Death & Disease

https://www.nature.com/articles/s41419-018-0635-5?fbclid=IwAR1TwR87xCmFCTrp
JXVF_MLCI8WwJ3ldqOuX244XeZuHmpGORmLNm8Ea934

Polydatin, Natural Precursor of Resveratrol, Promotes Osteogenic Differentiation of Mesenchymal Stem Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036093/

 



1 x mini Aspirin 80mg  ( just before bed)

being one tablet in water.
Metabolic Pathway inhibitors: Fatty Acids/ FAS

“Aspirin and dipyridamole, both antiplatelet drugs, synergistically serve to break down the platelet clumps and expose the abnormal macrophages to the rest of the immune system”

“The ‘acetyl’ part of aspirin (acetyl salicylic acid) binds to the amino acid serine”

Mclelland, Jane. How to Starve Cancer …without starving yourself: The Discovery of a Metabolic Cocktail That Could Transform the Lives of Millions . Conscious Dreams Publishing. Kindle Edition.

Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations.

https://www.ncbi.nlm.nih.gov/pubmed/23384979

Ray Peat, PhD on Aspirin – Functional Performance Systems (FPS)
https://www.functionalps.com/blog/2012/04/22/ray-peat-phd-on-aspirin/

https://cowseatgrass.org/2016/05/26/beware-when-rousing-the-bear-with-aspirin/?fbclid=IwAR103haIKFypLLQnzEgm0tjItVqWIOsiituVUNWOamiKG2x4G096v2mhD1U

I found this really interesting read in reference to reversing cancer with the help of high dose Aspirin.
http://www.fuckportioncontrol.com/blog/2016/12/21/cancer?rq=cancer&fbclid=IwAR17oqXoVReMDfy3gCzrazSQFjRiAGlxntSTh0TDO26jlRQaugDE66onqjM

Google: Nicotinamide (Vit  B3) protects the stomach mucus from damage caused by Aspirin


3 x Omega-7  450mg  (1 with each main meal)

being Sea Buckthorn Oil available online at  i-herb.com.
while I’m taking focusing on lowering cholesterol levels this is good oil.
https://www.sciencedirect.com/science/article/pii/S1756464611000028


Lots of Extra Virgin Olive Oil in breaky bowl & splashed on every meal

Modulation of inflammation and immunity by dietary conjugated linoleic acid



1 x Vitamin D3 5000iu with K2
(with b’fast)

being Colecalciferol and available online at  i-herb.com.

A phase 2 trial exploring the effects of high‐dose (10,000 IU/day) vitamin D3 in breast cancer patients with bone metastases
https://onlinelibrary.wiley.com/doi/full/10.1002/cncr.24749

more for Vit D3
https://www.nature.com/articles/s41598-018-27297-1

https://www.nature.com/articles/s12276-018-0038-9



2 x Delta-Fraction Tocotrienals 125mg (1 with b’fast, 1 w lunch)

 Only take when I’m not avoiding anti-oxidants that recycle glutithione.
as DeltaGOLDtm being 90% delta-trocotrienals and 10% gamma tocotrienals from Vitamin E.
Brand: Life Extension available online at  i-herb.com.
Tocotrienols and Cancer: From the State of the Art to Promising Novel Patents.

https://europepmc.org/abstract/med/30652648

More about why I take the  delta fraction tocotrienals with the Garcinia

https://www.cancertreatmentsresearch.com/another-weak-spot-of-many-cancer-cells-atp-citrate-lyase-inhibition/?fbclid=IwAR2K0dqZrDVhLibkNHndgYmgwYo0B5e7uJWx0sc8kLTGVEWt4qeFMM0GLik



1 x Loratadine (mid morning)

being 1 tiny 10mg tablet about 2 hrs after lunch
metabolic pathway:  Glutamine/Macropinocytosis
Available over the counter at my local pharmacy

Effects of antihistamine use on survival in breast cancer.

http://ascopubs.org/doi/abs/10.1200/JCO.2018.36.15_suppl.e12527

 



1 x Zinc tablet at night.

being Zinc amino acid chelate 100mg
Equiv elemental Zinc 20mg
Zinc sulfate monohydrate 68.7mg
Equiv elemental zinc 25mg
total elemental zinc 45mgB6 20mg
selenium 26 microgram
brand: Ethical Nutrients



1 x Vitamin B Complete Sustained Release (1 tablet with breakfast)

B complex available online at  i-herb.com.
B1 100mg,B2 80mg, B2 100mg,
B5 120mg,B6 75mg,Folic Acid 400mcg, B12 100mcg, Choline bitartrate 50mg, Inositol 50mg, Biotin 50mcg, Ascorbic Acid 200mg

 


 Iodine 

being potassium iodine available online at  i-herb.com.



Ginger Powder min 5g doses (all day with everything).

being organic ginger powder from online herb spice supplier

and available online at  i-herb.com.

I mix at least this amount (usually more) into my breakfast bowls and all teas and make sure it sits beside me at all meals.

Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells

https://www.sciencedirect.com/science/article/pii/S0955286307001337

Gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641128/


6g of Ascorbic Acid from 35ml Liposomal Vitamin C (around 4pm)

Australian made pure liposomal Vitamin C without alcohol or soy.  I not only take this but I have been making it to order for others living in Australia since 2017. www.highdosevitaminc.com.au

LipoNaturals make another very good Liposomal Vitain C that is free from nasties and it is available online at  i-herb.com.


1/2 teaspoon x Ashwagandha (Indian Ginseng) mixed in tea.

being Ashwagandha powder from online herb supplier austral herbs, mixed into my  herbal tea one time each day.  Ashwgandha is aloso available online at i-herb.com.


1 x Magnesium Chelate (after dinner)

available online at  i-herb.com


20mg of Melatonin about an hour or so before bed.

Melatonin–estrogen interactions in breast cancer
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1600-079X.2004.00207.x


I have also happily taken
200mg of a day Mebendazole
4 days on / 3 days off, each week for 6 weeks in early 2019.

Repurposing Drugs in Oncology (ReDO)—mebendazole as an anti-cancer agent
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096024/


Zolodex Implant 1 x monthly
I am also in a state of chemically induced menopause from a
GnRH Analogue called Goserlin

brand name:
Zolodex (3.6mg implant)

 

Prescribed by my oncologist and given to me by my GP’s nurse once a month. This drug inhibits my ovaries from creating hormones.


To save you time, I have placed all the items listed above that are available online at iherb.com in an iherb.com  shopping basket. You can change the currency from my currency to yours at the top of the iherb page and you delete what you already have at home from the basket. This is the link to the view of the shopping basket : iherb basket 



A list of Metabolic pathways I have inhibited :

My Glutamine Pathway Inhibitors
IGF-1
Goserlin (Zolodex) implant each month from oncologist

Gln OXPHOS
Berberine
(+ Niclosamide in draw in case of trouble)

mTOR:
Berberine

Macropinocytosis:
Loratadine
(+ Hydroxy Chloroquine in draw in case of trouble)

Nucleoside Salvage:
Dipyridamole

Glutaminolysis:
EGCG in Green Tea,
Curcumin phytosome with meriva.
washed down with Ursolic Acid in Tulsi Tea,
and a teaspoon of Japanese Knotweed aka Hu Zang root from which RESveratrol comes (see important warning below),

Walking a Tightrope: A Perspective of Resveratrol Effects on Brea…: Ingenta Connect

https://www.ingentaconnect.com/content/ben/cpps/2018/00000019/00000003/art00008

*Warning: not a safe supplement for everyone with breast cancer.. until you read this and your doctor agrees that it is not going to cause you harm in regards to estrogen do NOT take it.



Glucose Pathways Inhibited

Glut 1:
Quercetin,
Curcumin phytosome with meriva,
Liposomal vitC

Insulin:
Low GI Diet,
Walk after meal,
Berberine,

PP Pathway:
Keto-7 DHEA,
Japanese Knotweed aka Hu Zang root powder
again a warning goes with this supplement

Walking a Tightrope: A Perspective of Resveratrol Effects on Brea…: Ingenta Connect

https://www.ingentaconnect.com/content/ben/cpps/2018/00000019/00000003/art00008

*Warning: not a safe supplement for everyone with breast cancer.. until you read this and your doctor agrees that it is not going to cause you harm in regards to estrogen do NOT take it.

OxPhos:
Berberine

Aerobic Glycolosis
Liposomal Vitamin C


Fatty Acid Pathway Inhibitors
SREBP-1 Acetate:
Berberine

ACLY:
Garcinia Cambogia plus Alpha Lipoic Acid

F.A.S:
Mini Aspirin

F.A.O:

Nicotinamide ( flush free niacin) ,
Niacin
Avoiding rancid oils adding extra good olive oil, + omega 3, 6 and 7

SREBP-1:
Berberine

Mevolonate:
Citrus Bergamot

SREBP-2:
Dipyridamole

Abnormal Cell Signalling
Sonic Hedgehog

Abnormal in many cancers including breast cancer:

The role of the Hedgehog signaling pathway in cancer: A comprehensive review. – PubMed – NCBI

https://www.ncbi.nlm.nih.gov/pubmed/29274272

Inhibitors: Berberine, Metformin, Mebendazole

Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546096/

 

Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. – PubMed – NCBI

https://www.ncbi.nlm.nih.gov/pubmed/25999130

 

Multi-targeted therapy of cancer by niclosamide: a new application for an old drug

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166407/

 

WNT signaling deregulation induces bone metastases in breast cancer:


WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth
https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr2317

 

WNT Regulators: Aspirin, Dipyridamole, Niclosamide, Vitamin D3, NSAIDs,

A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963808/

Notch
Notch signaling has a role in breast cancer:

The Notch Pathway in Breast Cancer Progression

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077551/

Notch Regulators: Luteolin, Sulforaphane, Quercetin, Niclosamide

Mechanism of metastasis suppression by luteolin in breast cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003288/

Notch Activation Is Dispensable for D, L-Sulforaphane-Mediated Inhibition of Human Prostate Cancer Cell Migration
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044957

Notch Inhibitors for Cancer Treatment

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732476/


Toll Like Receptors (TLR’s) and Breast cancer: TLR’s-3, 4 & 9
Studies Indicate:
Berberine, Low dose naltrexone (LDN), and Hydroxychloroquine 

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis | BMC Cancer | Full Text
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-665

TLR4 Promotes Breast Cancer Metastasis via Akt/GSK3β/β-Catenin Pathway upon LPS Stimulation. – PubMed – NCBI
https://www.ncbi.nlm.nih.gov/pubmed/28296189

Berberine Modulates Gut Microbiota and Reduces Insulin Resistance via the TLR4 Signaling Pathway. – PubMed – NCBI
https://www.ncbi.nlm.nih.gov/pubmed/29365334

Low dose naltrexone (LDN) US20180207263A1 – Treatment of cancer with naltrexone – Google Patents
https://patents.google.com/patent/US20180207263A1/en

Hydroxychloroquine efficiently suppresses inflammatory responses of human class-switched memory B cells via Toll-like receptor 9 inhibition. – PubMed – NCBI https://www.ncbi.nlm.nih.gov/pubmed/29981383

Recent progress in the development of Toll-like receptor (TLR) antagonists: Expert Opinion on Therapeutic Patents: Vol 26, No 6
https://www.tandfonline.com/doi/abs/10.1080/13543776.2016.1185415


Integrins contribute to the development and progression of tumors in breast cancer
Studies indicate: Dipyridamole

Increased β1 Integrin Is Associated with Decreased Survival in Invasive Breast Cancer | Cancer Research
http://cancerres.aacrjournals.org/content/67/2/659.short

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies | JCB

http://jcb.rupress.org/content/137/1/231.abstract

Integrin activation controls metastasis in human breast cancer | PNAS
https://www.pnas.org/content/98/4/1853.short

Dipyridamole enhances an anti‐proliferative effect of interferon in various types of human tumor cells – Suzuki – 1992 – International Journal of Cancer – Wiley Online Library
https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.2910510420

Inhibition of Metastases by Anticoagulants | JNCI: Journal of the National Cancer Institute | Oxford Academic

https://academic.oup.com/jnci/article/91/1/22/2549


Estrogen is strongly linked to many breast cancers.
Studies indicate: Hormone therapies incl. Goserlin (my monthly Zolodex implant from my oncologist), Melatonin and Tocopherols

Melatonin is an appropriate candidate for breast cancer treatment: Based on known molecular mechanisms – Amin – 2019 – Journal of Cellular Biochemistry – Wiley Online Library
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.28832

Frontiers | Co-administering Melatonin with an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mammary Cancer Development in a Mouse Model of HER2-positive Breast Cancer | Oncology
https://www.frontiersin.org/articles/10.3389/fonc.2019.00525/abstract

Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-γ
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753525/



EGFR

Studies Indicate: Berberine, EGCG, Curcumin


Interleukins
are linked to progression in Breast Cancer
Studies Indicate: NSAID’s, Aspirin


PPAR In many cancers doesn’t contribute to start of Breast Cancer but does progress in later stages
Studies Indicate: Citrus Bergamot, Berberine , Fish oils (Omega-3), Vit -A and Vit-D and Sea Buckthorn Oil (Omega -7)

My “How to Starve Cancer… Study Support Group”
https://www.facebook.com/groups/starvecancer/ is a 2000+ member strong cancer study group (on Facebook). It is currently in secret mode so you will first need to find me on Facebook and make a friend request with an accompanying Facebook message that will let me know you want to join this study support group. A reply message will come directly from me. http://www.facebook.com/abbey.mitchell.71

Free 60 min Support Calls

Feeling overloaded and want book a support call with me?

I offer 60 minute Facetime support calls. Use the contact page to let me know your time zone and best days and times and the area in which you would love to receive some of my support. My own time zone is SYD, Australia AEST and I’m available between 8am – 8pm most days. I do not charge for my suport calls, and I am equally open to receiving a gift from you in return for my time. Any such gift can be made at your own discretion and in your own time; based entirely on whatever feels most comfortable and good for you to give, if it does after the call.
Abbey

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2019 – off to a flying start

Jan 2019
Celebrating: learning, co-operation, support & flow
My (Australian) GP approved my use of Dipyridamole yesterday. The chemist will be able to fulfill prescription next week. I will start with 100mg each day for a week and build up to 200mg each day of a slow release tablet.

I have been researching the power of Dipyridamole to inhibit the spread of cancer since I first learnt about it in Jane McLelland’s, How to Starve Cancer book.
Along with Glucosamine Sulphate, Mebendazole & Aspirin, this Dipyridamole will seal the deal when it comes to stopping the release of growth factors/enzymes (VEGF’s & MMP’s) that break down the extracellular matrix and could allow my cancer to spread and grow.

I will just need to keep an eye on my blood pressure levels and make sure it does not get too low. The out of pocket cost is very low, but I will report back when I pick up the script next week.

I can’t recommend Jane McLelland’s book highly enough. “How to starve cancer without starving yourself”. I’ve heard the paper version is out of stock currently but I highly recommend the Kindle version for easy note taking, high-lighting cross-referencing and further online researching. https://www.amazon.com.au/Starve-Cancer-without-starving-yourself-ebook/dp/B07B2XMLT9

 

I  recently started utilizing the information in the book titled

“How to Starve Cancer without Starving Yourself” by Jane McLelland

and the “McLelland Metro Map” which is explained within the book.


My hope is that this year’s blog entries
will provide information
to the people that are supporting me,
in understanding exactly what it is
I’m doing in an attempt to
heal myself.


I also hope
that the order and accessibility
of the information on this site supports
anyone walking alongside me
on their own healing journeys.

Nothing written here on this site should be perceived as medical advice.

Wow…just wow.

This is an inspiring blog post by Cheryse who’s walking this journey a few steps ahead of me with such inspiring grace. Thank-you Cheryse!

cherysesjourney

Have you ever had a season of life that was hard and you wondered what good could possibly come of it? Perhaps at the end of that season, or maybe months or years down the road, you were able to look back and see how that season, despite all of its hardships, resulted in something beautiful?

When we lived in Hawaii, we had the pleasure of enjoying seasons where MANY MANY caterpillars would invade our yards, both front and back, and a few times, when we could see they were getting ready to form a chrysalis on something dangerous (one of our kiddos’ bikes or climbing structure), we moved them to a safer place. A few times, we would move the caterpillar to a stick and lay it over a large jar. We would leave it on our lanai or bring it into the kitchen to watch it form its…

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Clear Intentions for 2019

 

Christmas 2018 Update:
On one hand, I’m celebrating many great test results received throughout 2018. An ultrasound in September showed three tumors across my chest wall have vanished completely and regular blood tests indicate my tumor markers are well and truly in the ‘normal persons’ range. My MRI and full body bone scans from December indicate my cancer is stable and possibly even retreating in one of my vertebrae.

I’m also feeling more determined then ever, that I can clear this cancer out of my body. I’m happy with my super healthy, balanced low-carb diet and energetically balanced life, my strong immune system; all have all been a great achievements, but I’m feeling like I’m now in the right place on all levels to totally slay this cancer dragon.

I have been fortunate that in the past week I found this new book by U.K cancer out- smarter, Jane McLelland. It’s really a must read for anyone looking to out-smart the dragon that is cancer. Jane has mapped the metabolic pathways of the cancer cells and ways to block these pathways using affordable re-purposed medications, (both over the counter and prescription), alongside close attention to diet and  timing specific exercise.

I’ll keep you updated to how I chose to engage with the new information I’m integrating from the book and how my body responds over the coming months.

I’ve stuck this image of the Goddess Kali to my fridge to inspire me throughout the new year.
Goddess-Kali-gods-of-hinduism-33227362-601-750

 

Protection against regular cancer screening procedures.

Here’s a link to a great interview for anyone with cancer to hear. It was most valuable for me to listen to, as I am booked in for both an MRI (with ‘no’ contrast fluids) of my spine and a full body bone scan on the same day to monitor my situation.
The role of high dose vitamin C to support us in protecting our healthy cells while living with cancer scanning appointments and conventional treatment choices is discussed.

16 Months after secondary breast cancer diagnosis

It’s now Nov 1st 2018 and my oncologist told me last week that my breast cancer tumor markers have dropped even further. They are now 16. I’m feeling magnificent and I will be getting an MRI of my spine next month to see how my Lumbar region is looking.
I’m currently not taking as many supplements as I was previously. This is what I’m taking currently:

I’m adding plenty of organic turmeric & ginger powder to breakfast, all cups of tea &  to my dinner. I drink organic Chrysanthemum tea with Marshmallow root with some organic ginger and turmeric powder in that too.

I am still loving my breakfast bowl of soaked chia, with 1 tspn chlorella powder, whole lemon juice to taste, soaked organic goji berries, 1 tspn organic ginger powder  & 1 tspn organic rose-hip powder. Lunches are organic vegetable salads with sauerkraut, sometimes mackerel or chicken & avocado with lightly toasted pumpkin seeds and sunflower seeds.

Over the past couple of months I have enjoyed reading the book Radical Remission and the book, Molecules of Emotion. Both have provided me with the opportunity to reflect more deeply on how my emotional state and my sub-conscious state (the body’s intelligence systems of information and energy we call the mind) influence my healing of secondary breast cancer and my ability to maintain my good health going forward.

I now know how to muscle test (communicate with my sub-conscious mind about my body’s needs), and for the past 6 weeks I have used  The Emotion Code to release trapped emotions from my body. I’ve found the releasing of trapped emotional baggage to be incredibly powerful. Physical conditions which I thought were never going to go away just left – And emotions which I thought were outside of my direct influence, left like a switch was flicked – gone!. I am so impressed with the power of this work that I am now completing The Emotion Code practitioner training so I can support others to release their emotional baggage that is causing stress in their bodies, their life  and in their relationships with others. We all deserve to feel this good!

I’m aiming to have completed my training by the end of 2018. As a part of my training requirements, I’m looking for volunteers for free sessions with me (November/ December 2018). So, if you are in pain or have a nagging physical condition that you just can’t seem to get over, or blocks to the kind of relationships or life you desire, please get in touch. It is very likely that trapped emotions are getting in the way of your full recovery, your total well-being & your alignment with your highest good.  Please contact me if you are interested in booking a free 45min Release Session with me in 2018. These can be done both via video call and in person.

I’ll check back in, in late December to share my  MRI results with you.
x Abbey